P. Leon Brown

Work

Maryland Psychiatric Research Center

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Assistant Professor

US

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Maryland Psychiatric Research Center

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Instructor

US

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Maryland Psychiatric Research Center

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Postdoctoral Fellow

US

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National Institute on Drug Abuse Intramural Research Program

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Research Associate

US

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Maryland Psychiatric Research Center

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Research Associate

US

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Education

University of Maryland Baltimore

United States of America
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Ph D

University of New Hampshire

United States of America
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MA

St. Lawrence University

United States of America
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BS

Publications

Functional Impairments in Learning and Signal Propagation Following Prenatal Kynurenine Treatment in Mice

European Journal of Neuroscience

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Functional Impairments in Learning and Signal Propagation Following Prenatal Kynurenine Treatment in Mice

European Journal of Neuroscience

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White matter and latency of visual evoked potentials during maturation: a miniature pig model of adolescent development.

Journal of neuroscience methods

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Substantia Nigra Dopamine Neuronal Responses to Habenular Stimulation and Foot Shock Are Altered by Lesions of the Rostromedial Tegmental Nucleus.

Neuroscience

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Quantitative and qualitative sex difference in habenula-induced inhibition of midbrain dopamine neurons in the rat.

Frontiers in behavioral neuroscience

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Isoflurane but Not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression?

The international journal of neuropsychopharmacology

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The rostromedial tegmental nucleus modulates the development of stress-induced helpless behavior.

Behavioural brain research

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Habenula-Induced Inhibition of Midbrain Dopamine Neurons Is Diminished by Lesions of the Rostromedial Tegmental Nucleus.

The Journal of neuroscience : the official journal of the Society for Neuroscience

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Engaging Research Domain Criteria (RDoC): Neurocircuitry in Search of Meaning.

Schizophrenia bulletin

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Functional evidence for a direct excitatory projection from the lateral habenula to the ventral tegmental area in the rat.

Journal of neurophysiology

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Manganese-Enhanced MRI Reflects Both Activity-Independent and Activity-Dependent Uptake within the Rat Habenulomesencephalic Pathway.

PloS one

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Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats.

PloS one

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Altered spatial learning, cortical plasticity and hippocampal anatomy in a neurodevelopmental model of schizophrenia-related endophenotypes.

The European journal of neuroscience

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Orbitofrontal inactivation impairs reversal of Pavlovian learning by interfering with 'disinhibition' of responding for previously unrewarded cues.

The European journal of neuroscience

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Ventral striatal neurons encode the value of the chosen action in rats deciding between differently delayed or sized rewards.

The Journal of neuroscience : the official journal of the Society for Neuroscience

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Sensory effects of intravenous cocaine on dopamine and non-dopamine ventral tegmental area neurons.

Brain research

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Brain edema and breakdown of the blood-brain barrier during methamphetamine intoxication: critical role of brain hyperthermia.

The European journal of neuroscience

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I.v. cocaine induces rapid, transient excitation of striatal neurons via its action on peripheral neural elements: single-cell, iontophoretic study in awake and anesthetized rats.

Neuroscience

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Procedure of rectal temperature measurement affects brain, muscle, skin, and body temperatures and modulates the effects of intravenous cocaine.

Brain research

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Relationships between locomotor activation and alterations in brain temperature during selective blockade and stimulation of dopamine transmission.

Neuroscience

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The role of peripheral and central sodium channels in mediating brain temperature fluctuations induced by intravenous cocaine.

Brain research

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The role of peripheral Na(+) channels in triggering the central excitatory effects of intravenous cocaine.

The European journal of neuroscience

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Brain temperature change and movement activation induced by intravenous cocaine delivered at various injection speeds in rats.

Psychopharmacology

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Dopamine-dependent and dopamine-independent actions of cocaine as revealed by brain thermorecording in freely moving rats.

The European journal of neuroscience

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Brain and body temperature homeostasis during sodium pentobarbital anesthesia with and without body warming in rats.

Physiology & behavior

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Fatal intra-brain heat accumulation induced by meth-amphetamine at normothermic conditions in rats

International Journal of Neuroprotection and Neuroregeneration

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Modulation of physiological brain hyperthermia by environmental temperature and impaired blood outflow in rats.

Physiology & behavior

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Brain hyperthermia induced by MDMA (ecstasy): modulation by environmental conditions.

The European journal of neuroscience

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Brain temperature fluctuations during passive vs. active cocaine administration: clues for understanding the pharmacological determination of drug-taking behavior.

Brain research

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Brain hyperthermia is induced by methamphetamine and exacerbated by social interaction.

The Journal of neuroscience : the official journal of the Society for Neuroscience

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Naloxone depresses cocaine self-administration and delays its initiation on the following day.

Neuroreport

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Fluctuations in neural activity during cocaine self-administration: clues provided by brain thermorecording.

Neuroscience

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Brain temperature fluctuation: a reflection of functional neural activation.

The European journal of neuroscience

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Behavioral analysis of stress controllability effects in a new swim stress paradigm.

Pharmacology, biochemistry, and behavior

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FG 7142- and restraint-induced alterations in the ataxic effects of alcohol and midazolam in rats are time dependent.

Pharmacology, biochemistry, and behavior

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Regulation of pharyngeal motility by FMRFamide and related peptides in the medicinal leech, Hirudo medicinalis.

Invertebrate neuroscience : IN

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P. Leon Brown